I have never installed iTunes on my work computer based on my experience with it on my home computers. It installs stuff that runs in background and now it installs a device driver for iPhone etc. My colleague who also has an iPhone installed the iTunes 8 today and it bricked the computer. It was the device driver that caused the trouble. It blue screens while booting. All afternoon he was trying to get it back to working. The last I saw him doing was trying to use system recovery. Not sure if it will work. While loading drivers, it is faults in KERNEL32.EXE.
For the past few days I have been postponing the update message from Apple Software Updater on my home computer. I think I will wait until the issues are completely resolved. I only recently rebuilt my computer to Vista. I do have completely PC backup though.